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HAUSP, a novel deubiquitinase for Rb – MDM2 the critical regulator

Tumor suppressor retinoblastoma-associated protein (Rb) is an important cell cycle regulator, arresting cells in early G1. It is commonly inactivated in cancers and its level is maintained during the cell cycle. Rb is regulated by various post-translational modifications such as phosphorylation, ace...

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Bibliografske podrobnosti
Main Authors: Bhattacharya, Seemana, Ghosh, Mrinal K
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149788/
https://ncbi.nlm.nih.gov/pubmed/24823443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12843
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