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Functional Analyses Reveal Extensive RRE Plasticity in Primary HIV-1 Sequences Selected under Selective Pressure

BACKGROUND: HIV-1 Rev response element (RRE) is a functional region of viral RNA lying immediately downstream to the junction of gp120 and gp41 in the env coding sequence. The RRE is essential for HIV replication and binds with the Rev protein to facilitate the export of viral mRNA from nucleus to c...

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Bibliografiske detaljer
Main Authors: Cunyat, Francesc, Beerens, Nancy, García, Elisabet, Clotet, Bonaventura, Kjems, Jørgen, Cabrera, Cecilia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149556/
https://ncbi.nlm.nih.gov/pubmed/25170621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106299
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