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Functional Analyses Reveal Extensive RRE Plasticity in Primary HIV-1 Sequences Selected under Selective Pressure

BACKGROUND: HIV-1 Rev response element (RRE) is a functional region of viral RNA lying immediately downstream to the junction of gp120 and gp41 in the env coding sequence. The RRE is essential for HIV replication and binds with the Rev protein to facilitate the export of viral mRNA from nucleus to c...

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Autors principals: Cunyat, Francesc, Beerens, Nancy, García, Elisabet, Clotet, Bonaventura, Kjems, Jørgen, Cabrera, Cecilia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149556/
https://ncbi.nlm.nih.gov/pubmed/25170621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106299
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