Prospective Study of the Evolution of Blood Lymphoid Immune Parameters during Dacarbazine Chemotherapy in Metastatic and Locally Advanced Melanoma Patients

BACKGROUND: The importance of immune responses in the control of melanoma growth is well known. However, the implication of these antitumor immune responses in the efficacy of dacarbazine, a cytotoxic drug classically used in the treatment of melanoma, remains poorly understood in humans. METHODS: I...

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Autors principals: Mignot, Grégoire, Hervieu, Alice, Vabres, Pierre, Dalac, Sophie, Jeudy, Geraldine, Bel, Blandine, Apetoh, Lionel, Ghiringhelli, François
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149472/
https://ncbi.nlm.nih.gov/pubmed/25170840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105907
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