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The vitamin B12 analog cobinamide is an effective hydrogen sulfide antidote in a lethal rabbit model
BACKGROUND AND PURPOSE: Hydrogen sulfide (H(2)S) is a highly toxic gas for which no effective antidotes exist. It acts, at least in part, by binding to cytochrome c oxidase, causing cellular asphyxiation and anoxia. We investigated the effects of three different ligand forms of cobinamide, a vitamin...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149338/ https://ncbi.nlm.nih.gov/pubmed/24716792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15563650.2014.904045 |
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