Testicular Niche Required for Human Spermatogonial Stem Cell Expansion

Prepubertal boys treated with high-dose chemotherapy do not have an established means of fertility preservation because no established in vitro technique exists to expand and mature purified spermatogonial stem cells (SSCs) to functional sperm in humans. In this study, we define and characterize the...

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Bibliographic Details
Main Authors: Smith, James F., Yango, Pamela, Altman, Eran, Choudhry, Shweta, Poelzl, Andrea, Zamah, Alberuni M., Rosen, Mitchell, Klatsky, Peter C., Tran, Nam D.
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2014
Subjects:
Enabling Technologies for Cell-Based Clinical Translation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149303/
https://ncbi.nlm.nih.gov/pubmed/25038247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2014-0045
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