An aminopepetidase in the Drosophila testicular niche acts in germline stem cell maintenance and spermatogonial dedifferentiation

Extrinsic cues from the niche are known to regulate adult stem cell self-renewal versus differentiation. Here we report that an aminopeptidase Slamdance (Sda) acts in the Drosophila testicular niche to maintain germline stem cells (GSCs) and regulate progenitor germ cell dedifferentiation. Mutations...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Lim, Cindy, Gandhi, Shiv, Biniossek, Martin L., Feng, Lijuan, Schilling, Oliver, Urban, Siniša, Chen, Xin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607668/
https://ncbi.nlm.nih.gov/pubmed/26440886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.001
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