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Targeting Cancer Stem Cell Plasticity Through Modulation of Epidermal Growth Factor and Insulin-Like Growth Factor Receptor Signaling in Head and Neck Squamous Cell Cancer
Emerging data suggest that cancer stem cells (CSCs) exist in equilibrium with differentiated cells and that stochastic transitions between these states can account for tumor heterogeneity and drug resistance. The aim of this study was to establish an in vitro system that recapitulates stem cell plas...
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Главные авторы: | , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
AlphaMed Press
2014
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149297/ https://ncbi.nlm.nih.gov/pubmed/25024430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0214 |
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