Targeting Cancer Stem Cell Plasticity Through Modulation of Epidermal Growth Factor and Insulin-Like Growth Factor Receptor Signaling in Head and Neck Squamous Cell Cancer

Emerging data suggest that cancer stem cells (CSCs) exist in equilibrium with differentiated cells and that stochastic transitions between these states can account for tumor heterogeneity and drug resistance. The aim of this study was to establish an in vitro system that recapitulates stem cell plas...

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Detalhes bibliográficos
Main Authors: Leong, Hui Sun, Chong, Fui Teen, Sew, Pui Hoon, Lau, Dawn P., Wong, Bernice H., Teh, Bin-Tean, Tan, Daniel S.W., Iyer, N. Gopalakrishna
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2014
Assuntos:
Cancer Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149297/
https://ncbi.nlm.nih.gov/pubmed/25024430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0214
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