Association between intensification of metformin treatment with insulin versus sulfonylureas and cardiovascular events and all-cause mortality among patients with diabetes

IMPORTANCE: Preferred second line medication for diabetes treatment after metformin failure remains uncertain. OBJECTIVE: We compared time to acute myocardial infarction [AMI], stroke, or death in a cohort of metformin initiators who added insulin or a sulfonylurea. DESIGN: Retrospective cohort cons...

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Main Authors: Roumie, Christianne L., Greevy, Robert A., Grijalva, Carlos G., Hung, Adriana M., Liu, Xulei, Murff, Harvey J., Elasy, Tom A., Griffin, Marie R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149288/
https://ncbi.nlm.nih.gov/pubmed/24915260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2014.4312
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