Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function

IMPORTANCE: Before 2016, safety concerns limited metformin use in patients with kidney disease; however, the effectiveness of metformin on clinical outcomes in patients with reduced kidney function remains unknown. OBJECTIVE: To compare major adverse cardiovascular events (MACE) among patients with...

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Pubblicato in:JAMA
Autori principali: Roumie, Christianne L., Chipman, Jonathan, Min, Jea Young, Hackstadt, Amber J., Hung, Adriana M., Greevy, Robert A., Grijalva, Carlos G., Elasy, Tom, Griffin, Marie R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2019
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Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753652/
https://ncbi.nlm.nih.gov/pubmed/31536102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.13206
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