Antagonistic effect of TNF-alpha and insulin on uncoupling protein 2 (UCP-2) expression and vascular damage

BACKGROUND: It has been reported that increased expression of UCP-2 in the vasculature may prevent the development of atherosclerosis in patients with increased production of reactive oxygen species, as in the diabetes, obesity or hypertension. Thus, a greater understanding in the modulation of UCP-...

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Bibliographic Details
Main Authors: Gómez-Hernández, Almudena, Perdomo, Liliana, de las Heras, Natalia, Beneit, Nuria, Escribano, Óscar, Otero, Yolanda F, Guillén, Carlos, Díaz-Castroverde, Sabela, Gozalbo-López, Beatriz, Cachofeiro, Victoria, Lahera, Vicente, Benito, Manuel
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149264/
https://ncbi.nlm.nih.gov/pubmed/25077985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-014-0108-9
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