Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes

BACKGROUND: Glucocorticoid receptor (GR) is a hormone-activated, DNA-binding transcriptional regulatory factor that controls inflammation, metabolism, stress responses, and other physiological processes. In vitro, GR binds as an inverted dimer to a motif consisting of two imperfectly palindromic 6 b...

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Detaylı Bibliyografya
Asıl Yazarlar: Schiller, Benjamin J, Chodankar, Rajas, Watson, Lisa C, Stallcup, Michael R, Yamamoto, Keith R
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149261/
https://ncbi.nlm.nih.gov/pubmed/25085117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0418-y
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