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Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes
BACKGROUND: Glucocorticoid receptor (GR) is a hormone-activated, DNA-binding transcriptional regulatory factor that controls inflammation, metabolism, stress responses, and other physiological processes. In vitro, GR binds as an inverted dimer to a motif consisting of two imperfectly palindromic 6 b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149261/ https://ncbi.nlm.nih.gov/pubmed/25085117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0418-y |
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