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Adoptive Therapy with Chimeric Antigen Receptor Modified T Cells of Defined Subset Composition

The ability to engineer T cells to recognize tumor cells through genetic modification with a synthetic chimeric antigen receptor has ushered in a new era in cancer immunotherapy. The most advanced clinical applications are in in targeting CD19 on B cell malignancies. The clinical trials of CD19 CAR...

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Main Authors: Riddell, Stanley R., Sommermeyer, Daniel, Berger, Carolina, Liu, Lingfeng (Steven), Balakrishnan, Ashwini, Salter, Alex, Hudecek, Michael, Maloney, David G., Turtle, Cameron J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149222/
https://ncbi.nlm.nih.gov/pubmed/24667960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000036
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