eIF2α phosphorylation bidirectionally regulates the switch from short to long-term synaptic plasticity and memory

The late phase of long-term potentiation (LTP) and memory (LTM) requires new gene expression but the molecular mechanisms that underlie these processes are not fully understood. Phosphorylation of eIF2α inhibits general translation and selectively stimulates translation of ATF4, a repressor of CREB-...

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Detalhes bibliográficos
Main Authors: Costa-Mattioli, Mauro, Gobert, Delphine, Stern, Elad, Gamache, Karine, Colina, Rodney, Cuello, Claudio, Sossin, Wayne, Kaufman, Randal, Pelletier, Jerry, Rosenblum, Kobi, Krnjević, Krešimir, Lacaille, Jean-Claude, Nader, Karim, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149214/
https://ncbi.nlm.nih.gov/pubmed/17418795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.01.050
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