High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients

BACKGROUND: Breast cancer is a heterogeneous disease with a highly variable clinical outcome in which both genetic and epigenetic changes have critical roles. We investigated tumor expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in relation with patient survival and tumor relaps...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Derr, Remco S, van Hoesel, Anneke Q, Benard, Anne, Goossens-Beumer, Inès J, Sajet, Anita, Dekker-Ensink, N Geeske, de Kruijf, Esther M, Bastiaannet, Esther, Smit, Vincent THBM, van de Velde, Cornelis JH, Kuppen, Peter JK
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148956/
https://ncbi.nlm.nih.gov/pubmed/25139823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-604
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg