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β-III Tubulin Fragments Inhibit α-Synuclein Accumulation in Models of Multiple System Atrophy
Multiple system atrophy (MSA) is a neurodegenerative disease caused by α-synuclein aggregation in oligodendrocytes and neurons. Using a transgenic mouse model overexpressing human α-synuclein in oligodendrocytes, we previously demonstrated that oligodendrocytic α-synuclein inclusions induce neuronal...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148865/ https://ncbi.nlm.nih.gov/pubmed/25028513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557215 |
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