Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemia

The comprehensive genetic alterations underlying the pathogenesis of T-cell prolymphocytic leukemia (T-PLL) are unknown. To address this, we performed whole-genome sequencing (WGS), whole-exome sequencing (WES), high-resolution copy-number analysis, and Sanger resequencing of a large cohort of T-PLL...

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Hauptverfasser: Kiel, Mark J., Velusamy, Thirunavukkarasu, Rolland, Delphine, Sahasrabuddhe, Anagh A., Chung, Fuzon, Bailey, Nathanael G., Schrader, Alexandra, Li, Bo, Li, Jun Z., Ozel, Ayse B., Betz, Bryan L., Miranda, Roberto N., Medeiros, L. Jeffrey, Zhao, Lili, Herling, Marco, Lim, Megan S., Elenitoba-Johnson, Kojo S. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2014
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148768/
https://ncbi.nlm.nih.gov/pubmed/24825865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-559542
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