A multicenter, randomized, open-labeled study to steer immunosuppressive and antiviral therapy by measurement of virus (CMV, ADV, HSV)-specific T cells in addition to determination of trough levels of immunosuppressants in pediatric kidney allograft recipients (IVIST01-trial): study protocol for a randomized controlled trial

BACKGROUND: After kidney transplantation, immunosuppressive therapy causes impaired cellular immune defense leading to an increased risk of viral complications. Trough level monitoring of immunosuppressants is insufficient to estimate the individual intensity of immunosuppression. We have already sh...

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Detaylı Bibliyografya
Asıl Yazarlar: Ahlenstiel-Grunow, Thurid, Koch, Armin, Großhennig, Anika, Frömke, Cornelia, Sester, Martina, Sester, Urban, Schröder, Christoph, Pape, Lars
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Study Protocol
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148534/
https://ncbi.nlm.nih.gov/pubmed/25127887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-15-324
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