A multicenter, randomized, open-labeled study to steer immunosuppressive and antiviral therapy by measurement of virus (CMV, ADV, HSV)-specific T cells in addition to determination of trough levels of immunosuppressants in pediatric kidney allograft recipients (IVIST01-trial): study protocol for a randomized controlled trial

BACKGROUND: After kidney transplantation, immunosuppressive therapy causes impaired cellular immune defense leading to an increased risk of viral complications. Trough level monitoring of immunosuppressants is insufficient to estimate the individual intensity of immunosuppression. We have already sh...

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Detalhes bibliográficos
Main Authors: Ahlenstiel-Grunow, Thurid, Koch, Armin, Großhennig, Anika, Frömke, Cornelia, Sester, Martina, Sester, Urban, Schröder, Christoph, Pape, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148534/
https://ncbi.nlm.nih.gov/pubmed/25127887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-15-324
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