Tumor Suppressor MicroRNA-27a in Colorectal Carcinogenesis and Progression by Targeting SGPP1 and Smad2

The aberrant expression of microRNAs (miRNAs) is associated with colorectal carcinogenesis, but the underlying mechanisms are not clear. This study showed that the miRNA-27a (miR-27a) was significantly reduced in colorectal cancer tissues and colorectal cancer cell lines, and that the reduced miR-27...

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Bibliografiska uppgifter
Huvudupphovsmän: Bao, Yonghua, Chen, Zhiguo, Guo, Yongchen, Feng, Yansheng, Li, Zexin, Han, Wenliang, Wang, Jianguo, Zhao, Weixing, Jiao, Yunjuan, Li, Kai, Wang, Qian, Wang, Jiaqi, Zhang, Huijuan, Wang, Liang, Yang, Wancai
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148394/
https://ncbi.nlm.nih.gov/pubmed/25166914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105991
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