Tumor Suppressor MicroRNA-27a in Colorectal Carcinogenesis and Progression by Targeting SGPP1 and Smad2

The aberrant expression of microRNAs (miRNAs) is associated with colorectal carcinogenesis, but the underlying mechanisms are not clear. This study showed that the miRNA-27a (miR-27a) was significantly reduced in colorectal cancer tissues and colorectal cancer cell lines, and that the reduced miR-27...

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Bibliografiske detaljer
Main Authors: Bao, Yonghua, Chen, Zhiguo, Guo, Yongchen, Feng, Yansheng, Li, Zexin, Han, Wenliang, Wang, Jianguo, Zhao, Weixing, Jiao, Yunjuan, Li, Kai, Wang, Qian, Wang, Jiaqi, Zhang, Huijuan, Wang, Liang, Yang, Wancai
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148394/
https://ncbi.nlm.nih.gov/pubmed/25166914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105991
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