Bioengineered Vaults: Self-Assembling Protein Shell–Lipophilic Core Nanoparticles for Drug Delivery

[Image: see text] We report a novel approach to a new class of bioengineered, monodispersed, self-assembling vault nanoparticles consisting of a protein shell exterior with a lipophilic core interior designed for drug and probe delivery. Recombinant vaults were engineered to contain a small amphipat...

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Autors principals: Buehler, Daniel C., Marsden, Matthew D., Shen, Sean, Toso, Daniel B., Wu, Xiaomeng, Loo, Joseph A., Zhou, Z. Hong, Kickhoefer, Valerie A., Wender, Paul A., Zack, Jerome A., Rome, Leonard H.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148163/
https://ncbi.nlm.nih.gov/pubmed/25061969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn5002694
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