Bioengineered Vaults: Self-Assembling Protein Shell–Lipophilic Core Nanoparticles for Drug Delivery

[Image: see text] We report a novel approach to a new class of bioengineered, monodispersed, self-assembling vault nanoparticles consisting of a protein shell exterior with a lipophilic core interior designed for drug and probe delivery. Recombinant vaults were engineered to contain a small amphipat...

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Bibliografiska uppgifter
Huvudupphovsmän: Buehler, Daniel C., Marsden, Matthew D., Shen, Sean, Toso, Daniel B., Wu, Xiaomeng, Loo, Joseph A., Zhou, Z. Hong, Kickhoefer, Valerie A., Wender, Paul A., Zack, Jerome A., Rome, Leonard H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2014
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148163/
https://ncbi.nlm.nih.gov/pubmed/25061969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn5002694
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