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Ultrafast Water Dynamics at the Interface of the Polymerase–DNA Binding Complex

[Image: see text] DNA polymerases slide on DNA during replication, and the interface must be mobile for various conformational changes. The role of lubricant interfacial water is not understood. In this report, we systematically characterize the water dynamics at the interface and in the active site...

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Autors principals: Yang, Yi, Qin, Yangzhong, Ding, Qing, Bakhtina, Marina, Wang, Lijuan, Tsai, Ming-Daw, Zhong, Dongping
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148141/
https://ncbi.nlm.nih.gov/pubmed/25105470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500810a
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