Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal model

The human sulfatase 1 (hSulf-1) gene encodes an endosulfatase that functions to inhibit the heparin-binding growth factor signaling, including the basic fibroblast growth factor (bFGF)-mediated pathway, by desulfating the cell surface heparan sulfate proteoglycans (HSPGs). bFGF could stimulate cell...

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Detalhes bibliográficos
Main Authors: Xu, Gaoya, Ji, Weidan, Su, Yinghan, Xu, Yang, Yan, Yan, Shen, Shuwen, Li, Xiaoya, Sun, Bin, Qian, Haihua, Chen, Lei, Fu, Xiaohui, Wu, Mengchao, Su, Changqing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148119/
https://ncbi.nlm.nih.gov/pubmed/24970807
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