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Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats
To understand the mechanism by which early insulin therapy improves insulin sensitivity in type 2 diabetes, we investigated endoplasmic reticulum (ER) stress in the liver of type 2 diabetic rats. A high fat diet plus a low dose of streptozotocin (STZ) in Sprague–Dawley (SD) rats was implemented to c...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148044/ https://ncbi.nlm.nih.gov/pubmed/21088934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-010-9429-y |
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