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Functional Role of Glucose Metabolism, Osmotic Stress, and Sodium-Glucose Cotransporter Isoform-Mediated Transport on Na(+)/H(+) Exchanger Isoform 3 Activity in the Renal Proximal Tubule

Na(+)-glucose cotransporter 1 (SGLT1)-mediated glucose uptake leads to activation of Na(+)-H(+) exchanger 3 (NHE3) in the intestine by a process that is not dependent on glucose metabolism. This coactivation may be important for postprandial nutrient uptake. However, it remains to be determined whet...

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Autores principales: Pessoa, Thaissa Dantas, Campos, Luciene Cristina Gastalho, Carraro-Lacroix, Luciene, Girardi, Adriana C.C., Malnic, Gerhard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147971/
https://ncbi.nlm.nih.gov/pubmed/24652792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013060588
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