TGF-β–Activated Kinase 1 Is Crucial in Podocyte Differentiation and Glomerular Capillary Formation

TGF-β–activated kinase 1 (TAK1) is a key intermediate in signal transduction induced by TGF-β or inflammatory cytokines, such as TNF-α and IL-1, which are potent inducers of podocyte injury responses that lead to proteinuria and glomerulosclerosis. Nevertheless, little is known about the physiologic...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Sung Il, Lee, So-Young, Wang, Zhibo, Ding, Yan, Haque, Nadeem, Zhang, Jiwang, Zhou, Jing, Choi, Mary E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2014
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147968/
https://ncbi.nlm.nih.gov/pubmed/24652804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013030252
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