Differences in Fat and Muscle Mass Associated With a Functional Human Polymorphism in a Post-Transcriptional BMP2 Gene Regulatory Element

A classic morphogen, bone morphogenetic protein 2 (BMP2) regulates the differentiation of pluripotent mesenchymal cells. High BMP2 levels promote osteogenesis or chondrogenesis and low levels promote adipogenesis. BMP2 inhibits myogenesis. Thus, BMP2 synthesis is tightly controlled. Several hundred...

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書誌詳細
主要な著者: Devaney, Joseph M., Tosi, Laura L., Fritz, David T., Gordish-Dressman, Heather A., Jiang, Shan, Orkunoglu-Suer, Funda E., Gordon, Andrew H., Harmon, Brennan T., Thompson, Paul D., Clarkson, Priscilla M., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Brandoli, Cinzia, Hoffman, Eric P., Rogers, Melissa B.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147943/
https://ncbi.nlm.nih.gov/pubmed/19492344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22209
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