Differences in Fat and Muscle Mass Associated With a Functional Human Polymorphism in a Post-Transcriptional BMP2 Gene Regulatory Element

A classic morphogen, bone morphogenetic protein 2 (BMP2) regulates the differentiation of pluripotent mesenchymal cells. High BMP2 levels promote osteogenesis or chondrogenesis and low levels promote adipogenesis. BMP2 inhibits myogenesis. Thus, BMP2 synthesis is tightly controlled. Several hundred...

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Κύριοι συγγραφείς: Devaney, Joseph M., Tosi, Laura L., Fritz, David T., Gordish-Dressman, Heather A., Jiang, Shan, Orkunoglu-Suer, Funda E., Gordon, Andrew H., Harmon, Brennan T., Thompson, Paul D., Clarkson, Priscilla M., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Brandoli, Cinzia, Hoffman, Eric P., Rogers, Melissa B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2009
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Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147943/
https://ncbi.nlm.nih.gov/pubmed/19492344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22209
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