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The prognostic value of BRCA1 promoter methylation in early stage triple negative breast cancer
INTRODUCTION: Methylation of the BRCA1 promoter is frequent in triple negative breast cancers (TNBC) and results in a tumor phenotype similar to BRCA1-mutated tumors. BRCA1 mutation-associated cancers are more sensitive to DNA damaging agents as compared to conventional chemotherapy agents. It is no...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4147783/ https://ncbi.nlm.nih.gov/pubmed/25177489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7243/2049-7962-3-2 |
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