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Mechanisms of HIV Protein Degradation into Epitopes: Implications for Vaccine Design

The degradation of HIV-derived proteins into epitopes displayed by MHC-I or MHC-II are the first events leading to the priming of HIV-specific immune responses and to the recognition of infected cells. Despite a wealth of information about peptidases involved in protein degradation, our knowledge of...

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Detalhes bibliográficos
Main Authors: Rucevic, Marijana, Boucau, Julie, Dinter, Jens, Kourjian, Georgio, Le Gall, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147695/
https://ncbi.nlm.nih.gov/pubmed/25196483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6083271
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