Transformation of mammalian cells by overexpressing H2O2-generating peroxisomal fatty acyl-CoA oxidase.

Peroxisome proliferators induce qualitatively predictable pleiotropic responses, including development of hepatocellular carcinomas in rats and mice despite the inability of these compounds to interact with and damage DNA directly. In view of the nongenotoxic nature of peroxisome proliferators, it h...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Chu, S, Huang, Q, Alvares, K, Yeldandi, A V, Rao, M S, Reddy, J K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7624373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.7080
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