Transformation of mammalian cells by overexpressing H2O2-generating peroxisomal fatty acyl-CoA oxidase.

Peroxisome proliferators induce qualitatively predictable pleiotropic responses, including development of hepatocellular carcinomas in rats and mice despite the inability of these compounds to interact with and damage DNA directly. In view of the nongenotoxic nature of peroxisome proliferators, it h...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chu, S, Huang, Q, Alvares, K, Yeldandi, A V, Rao, M S, Reddy, J K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7624373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.15.7080
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