PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia

Pancreatic differentiation 2 (PD2), a PAF (RNA Polymerase II Associated Factor) complex subunit, is overexpressed in pancreatic cancer cells and has demonstrated potential oncogenic property. Here, we report that PD2/Paf1 expression was restricted to acinar cells in the normal murine pancreas, but i...

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Autors principals: Dey, Parama, Rachagani, Satyanarayana, Vaz, Arokia P., Ponnusamy, Moorthy P., Batra, Surinder K.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147339/
https://ncbi.nlm.nih.gov/pubmed/24947474
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