Insulin Preconditioning Elevates p-Akt and Cardiac Contractility after Reperfusion in the Isolated Ischemic Rat Heart

Insulin induces cardioprotection partly via an antiapoptotic effect. However, the optimal timing of insulin administration for the best quality cardioprotection remains unclear. We tested the hypothesis that insulin administered prior to ischemia provides better cardioprotection than insulin adminis...

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Detalhes bibliográficos
Main Authors: Sato, Tamaki, Sato, Hiroaki, Oguchi, Takeshi, Fukushima, Hisashi, Carvalho, George, Lattermann, Ralph, Matsukawa, Takashi, Schricker, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147204/
https://ncbi.nlm.nih.gov/pubmed/25197648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/536510
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