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Activation of salt shock response leads to solubilisation of mutant huntingtin in Saccharomyces cerevisiae

Formation of cytoplasmic and nuclear aggregates is a hallmark of Huntington’s disease (HD). Inhibition of aggregation of mutant huntingtin has been suggested to be a feasible approach to slow down the progress of this neurodegenerative disorder. Exposure to environmental stimuli leads to the activat...

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Bibliografske podrobnosti
Main Authors: Saleh, Aliabbas A., Bhadra, Ankan Kumar, Roy, Ipsita
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147074/
https://ncbi.nlm.nih.gov/pubmed/24464493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0492-9
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