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Activation of salt shock response leads to solubilisation of mutant huntingtin in Saccharomyces cerevisiae
Formation of cytoplasmic and nuclear aggregates is a hallmark of Huntington’s disease (HD). Inhibition of aggregation of mutant huntingtin has been suggested to be a feasible approach to slow down the progress of this neurodegenerative disorder. Exposure to environmental stimuli leads to the activat...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Netherlands
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4147074/ https://ncbi.nlm.nih.gov/pubmed/24464493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0492-9 |
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