Quasispecies evolution in NS5A region of hepatitis C virus genotype 1b during interferon or combined interferon-ribavirin therapy

AIM: To evaluate the implication of substitutions in the hepatitis C virus (HCV) non-structural 5A (NS5A) protein in the resistance of HCV during mono-interferon (IFN) or combined IFN-ribavirin (IFN-R) therapy. Although NS5A has been reported to interact with the HCV RNA-dependent RNA polymerase, NS...

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Autors principals: Veillon, Pascal, Payan, Christopher, Le Guillou-Guillemette, Hélène, Gaudy, Catherine, Lunel, Françoise
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2007
Matèries:
Viral Hepatitis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146993/
https://ncbi.nlm.nih.gov/pubmed/17451199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i8.1195
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