Mutations within the Hepatitis C Virus Genotype 1b E2-PePHD Domain Do Not Correlate with Treatment Outcome

The hepatitis C virus (HCV) envelope protein 2 (E2) interacts in vitro with the interferon alpha (IFN-α)-inducible double-stranded RNA-activated protein kinase, suggesting a possible mechanism by which HCV may evade the antiviral effects of IFN-α. Variability in the part of the HCV E2 gene encoding...

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Detalhes bibliográficos
Main Authors: Gaudy, Catherine, Lambelé, Marie, Moreau, Alain, Veillon, Pascal, Lunel, Francoise, Goudeau, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548054/
https://ncbi.nlm.nih.gov/pubmed/15695675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.2.750-754.2005
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