KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro

AIM: To investigate the effects of KN-93, a CaMKII selective inhibitor on cell proliferation and the expression of p53 or p21 protein in human hepatic stellate cells. METHODS: Human hepatic stellate cells (LX-2) were incubated with various concentrations (0-50 μmol/L) of KN-93 or its inactive deriva...

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Detalhes bibliográficos
Main Authors: An, Ping, Zhu, Jun-Yong, Yang, Yan, Lv, Peng, Tian, Yi-Hao, Chen, Ming-Kai, Luo, He-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146932/
https://ncbi.nlm.nih.gov/pubmed/17457979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i9.1445
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