Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling

Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene have been identified in a neurodevelopmental disorder characterized by early-onset intractable seizures, severe developmental delay, intellectual disability, and Rett's syndrome-like features. Since the physiological function...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fuchs, Claudia, Trazzi, Stefania, Torricella, Roberta, Viggiano, Rocchina, De Franceschi, Marianna, Amendola, Elena, Gross, Cornelius, Calzà, Laura, Bartesaghi, Renata, Ciani, Elisabetta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Academic Press 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146476/
https://ncbi.nlm.nih.gov/pubmed/24952363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.06.006
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