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The IL18RAP Region Disease Polymorphism Decreases IL-18RAP/IL-18R1/IL-1R1 Expression and Signaling Through Innate Receptor-Initiated Pathways
Fine-tuning of cytokine-inducing pathways is essential for immune homeostasis. Consistently, a dysregulated increase or decrease in pattern recognition receptors (PRR)-induced signaling and cytokine secretion can lead to inflammatory bowel disease (IBD). Multiple gene loci are associated with IBD, b...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146459/ https://ncbi.nlm.nih.gov/pubmed/24842757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302727 |
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