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Allopurinol reduces levels of urate and dopamine but not dopaminergic neurons in a dual pesticide model of Parkinson’s disease
Robust epidemiological data link higher levels of the antioxidant urate to a reduced risk of developing Parkinson’s disease (PD) and to a slower rate of its progression. Allopurinol, an inhibitor of xanthine oxidoreductase (XOR), blocks the oxidation of xanthine to urate. The present study sought to...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146456/ https://ncbi.nlm.nih.gov/pubmed/24680743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.03.031 |
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