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Molecular mechanisms of neuronal nitric oxide synthase in cardiac function and pathophysiology
Neuronal nitric oxide synthase (nNOS or NOS1) is the major endogenous source of myocardial nitric oxide (NO), which facilitates cardiac relaxation and modulates contraction. In the healthy heart it regulates intracellular Ca(2+), signalling pathways and oxidative homeostasis and is upregulated from...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146369/ https://ncbi.nlm.nih.gov/pubmed/24756636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.270306 |
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