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Molecular mechanisms of neuronal nitric oxide synthase in cardiac function and pathophysiology

Neuronal nitric oxide synthase (nNOS or NOS1) is the major endogenous source of myocardial nitric oxide (NO), which facilitates cardiac relaxation and modulates contraction. In the healthy heart it regulates intracellular Ca(2+), signalling pathways and oxidative homeostasis and is upregulated from...

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Detalhes bibliográficos
Main Authors: Zhang, Yin Hua, Jin, Chun Zi, Jang, Ji Hyun, Wang, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146369/
https://ncbi.nlm.nih.gov/pubmed/24756636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.270306
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