ROS and endothelial nitric oxide synthase (eNOS)-dependent trafficking of angiotensin II type 2 receptor begets neuronal NOS in cardiac myocytes

Angiotensin II (Ang II), a potent precursor of hypertrophy and heart failure, upregulates neuronal nitric oxide synthase (nNOS or NOS1) in the myocardium. Here, we investigate the involvement of type 1 and 2 angiotensin receptors (AT1R and AT2R) and molecular mechanisms mediating Ang II-upregulation...

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Detalhes bibliográficos
Publicado no:Basic Res Cardiol
Main Authors: Jang, Ji Hyun, Chun, Jung Nyeo, Godo, Shigeo, Wu, Guangyu, Shimokawa, Hiroaki, Jin, Chun Zi, Jeon, Ju Hong, Kim, Sung Joon, Jin, Zhe Hu, Zhang, Yin Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827156/
https://ncbi.nlm.nih.gov/pubmed/25804308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-015-0477-6
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