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The Influence of Trp53 in the Dose Response of Radiation-Induced Apoptosis, DNA Repair and Genomic Stability in Murine Haematopoietic Cells
Apoptotic and DNA damage endpoints are frequently used as surrogate markers of cancer risk, and have been well-studied in the Trp53+/− mouse model. We report the effect of differing Trp53 gene status on the dose response of ionizing radiation exposures (0.01–2 Gy), with the unique perspective of det...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Hormesis Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146330/ https://ncbi.nlm.nih.gov/pubmed/25249831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2203/dose-response.14-008.Lemon |
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