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A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis
Hypoxia-inducible factor 1 (HIF-1) attenuates amyloid-beta protein neurotoxicity and decreases apoptosis induced by oxidative stress or hypoxia in cortical neurons. In this study, we constructed a recombinant adeno-associated virus (rAAV) vector expressing the human HIF-1α gene (rAAV-HIF-1α), and te...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Medknow Publications & Media Pvt Ltd
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146100/ https://ncbi.nlm.nih.gov/pubmed/25206774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.135317 |
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