Targeting mTOR dependency in pancreatic cancer

OBJECTIVE: Pancreatic cancer is a leading cause of cancer-related death in the Western world. Current chemotherapy regimens have modest survival benefit. Thus, novel, effective therapies are required for treatment of this disease. DESIGN: Activating KRAS mutation almost always drives pancreatic tumo...

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Bibliographic Details
Main Authors: Morran, Douglas C, Wu, Jianmin, Jamieson, Nigel B, Mrowinska, Agata, Kalna, Gabriela, Karim, Saadia A, Au, Amy Y M, Scarlett, Christopher J, Chang, David K, Pajak, Malgorzata Z, Oien, Karin A, McKay, Colin J, Carter, C Ross, Gillen, Gerry, Champion, Sue, Pimlott, Sally L, Anderson, Kurt I, Evans, T R Jeffry, Grimmond, Sean M, Biankin, Andrew V, Sansom, Owen J, Morton, Jennifer P
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2014
Subjects:
Pancreas
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145424/
https://ncbi.nlm.nih.gov/pubmed/24717934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306202
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